“The E450 is in a class of its own and sets the driver apart from all other vehicles in any class, not just its own. Reliability, looks, handling, economy, and the pure thrill of a Mercedes E450 4matic. Just hold on to the steering wheel and accelerate into driving pleasure.”
2022 Mercedes-Benz E-Class: What's New, Specs & Features
Last updated August 4, 2026
The 2022 E-Class is a light-update year, led by automatic high-beam headlights becoming standard across the lineup. Otherwise, its engines, body styles, and overall trim structure carry over from 2021.
About the 2022 Mercedes-Benz E-Class
5th generation E-Class family for the U.S. (W213 sedan, S213 wagon, C238 coupe, A238 cabriolet), second model year after the 2021 refresh.
Mercedes positions the E-Class as its midsize luxury sweet spot: more polished and substantial than a compact luxury car, but easier to live with than a flagship sedan. In 2022, the range covers sedan, coupe, cabriolet, and wagon body styles, pairing a calm highway ride, a rich cabin, and strong safety tech with either efficient four-cylinder power or a smoother six-cylinder option. Its standout trait is breadth—there is an E-Class for traditional luxury-sedan shoppers, style-focused coupe buyers, open-air drivers, and wagon owners who want SUV-like usefulness without giving up a car-like drive.
The E 350 is the traditional luxury-sedan entry point, with a 255-hp turbo four-cylinder, a 12.3-inch touchscreen with navigation, heated front seats, and core driver-assistance features. The 362-hp E 450 brings a stronger inline-six and spans sedan, wagon, coupe, and cabriolet body styles, while all-wheel-drive versions add extra traction. The rear-wheel-drive E 450 coupe and cabriolet stand out with leather upholstery and Burmester surround-sound audio.
What changed, by category
Safety
Automatic high-beam headlights became standard across the 2022 E-Class lineup.
2022 Mercedes-Benz E-Class specs and features by trim
| Feature | ||||
|---|---|---|---|---|
| Engine | 4-Cyl, Turbo, 2.0 Liter | 6-Cyl, Turbo, 3.0 Liter w/EQ Boost | 4-Cyl, Turbo, 2.0 Liter | 6-Cyl, Turbo, 3.0 Liter w/EQ Boost |
| Transmission | Automatic, 9-Spd 9G-Tronic | Automatic, 9-Spd 9G-Tronic | Automatic, 9-Spd 9G-Tronic | Automatic, 9-Spd 9G-Tronic |
| Drivetrain | RWD | RWD | AWD | AWD |
| Fuel Type | Gas | Gas | Gas | Gas |
| MPG City | 23 mpg | 22 mpg | 21 mpg | 21–23 mpg |
| MPG Highway | 31 mpg | 29 mpg | 29 mpg | 28–30 mpg |
| Horsepower | 255 hp | 362 hp | 255 hp | 362 hp |
| Torque | 273 lb-ft | 369 lb-ft | 273 lb-ft | 369 lb-ft |
| Trunk/Cargo | 13.1 cu-ft | 9.5–10 cu-ft | 13.1 cu-ft | 9.5–35 cu-ft |
| Rear Legroom | 36.1 in | 34.1–35.9 in | 36.1 in | 34.1–36.1 in |
| Seats | 5 | 4 | 5 | 4–7 |
| Doors | 4 | 2 | 4 | 2–4 |
| Adaptive Headlights | ||||
| Alarm System | ||||
| Automatic Emergency Braking | ||||
| Automatic High Beams | ||||
| Blindspot Sensors | ||||
| Lane Departure Warning | ||||
| Park Assist | ||||
| Rear View Camera | ||||
| 360 Camera | ||||
| Alloy Wheels | ||||
| LED Headlights | ||||
| Power Moonroof | ||||
| Panorama Moon Roof | ||||
| Power Retractable Soft Top | ||||
| Rear Spoiler | ||||
| Navigation System | ||||
| Premium Audio | ||||
| Smartphone Interface | ||||
| 115V Power Outlet | ||||
| Dual-Zone Climate Control | ||||
| Rear Air Conditioning | ||||
| Heated Front Seats | ||||
| Heated Rear Seats | ||||
| Heated Steering Wheel | ||||
| Leather Seats | ||||
| Rear Window Shades | ||||
| Remote Start | ||||
| Third Row Seat | ||||
| Ventilated Front Seats | ||||
Frequently asked questions
What changed on the 2022 Mercedes-Benz E-Class?
Automatic high-beam headlights became standard across the 2022 E-Class lineup. Beyond that equipment update, the engines, body styles, and general trim structure remained largely unchanged from 2021.
Is the 2022 Mercedes-Benz E-Class a redesign?
No, the 2022 E-Class is not a redesign. It is the second model year after the major 2021 refresh and receives only a small equipment update.
Does every 2022 Mercedes-Benz E-Class have automatic high-beam headlights?
Yes, automatic high-beam headlights are standard across the 2022 E-Class range. They automatically switch between high and low beams when conditions allow.
Did the engines change for the 2022 Mercedes-Benz E-Class?
No, the main engines carried over for 2022. The E 350 sedan uses a 255-hp turbocharged four-cylinder, while E 450 models use a 362-hp turbocharged inline-six.
Is the 2022 Mercedes-Benz E-Class worth considering over the 2021 model?
The 2022 model mainly makes sense if standard automatic high-beam headlights matter to you. Otherwise, it is very similar to the refreshed 2021 E-Class in powertrains, body styles, and overall trim structure.
2022 Mercedes-Benz E-Class Reviews
What owners are saying about the 2022 Mercedes-Benz E-Class.
4.3
2022 Mercedes-Benz E-Class
(712 reviews)
“It is a little tight getting in and out of this vehicle but once you are in it is a lot of fun to drive.”
“Beware of all the accessories; some are helpful and some you may not only not want but are annoying!”