| Includes | IS 200t, IS 250, IS 250 Sport, IS 250C, IS 30072 in stock | IS 500 F SPORT Performance, IS 500 F SPORT Performance Launch Edition, IS 500 F SPORT Performance Premium, IS 500 F SPORT Performance Ultimate Edition, IS F1 in stock | IS 350, IS 350 F SPORT, IS 350 F SPORT Design, IS 350 Sport, IS 350C61 in stock | | |
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| Engine identity | Turbo four-cylinder or V6; varies by member | 5.0-liter V8 | 3.5-liter V6 | IS 300 turbo four-cylinder or V6 | 2.5-liter V6 |
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| Horsepower by member | 204–260 hp | IS 500: 472 hp; IS F: 5.0L V8 | 306 hp older; 311 hp newer | 241 hp RWD; 260 hp AWD | 204 hp |
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| Sport appearance | Standard IS look | IS F or F SPORT Performance themes | Regular or F SPORT, by member | F SPORT exterior | Exclusive black-and-white F SPORT look |
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| Suspension focus | Everyday sport-sedan tuning | Adaptive or track-focused performance tuning | Sport-tuned on full F SPORT | Standard on Design; sport-tuned on full F SPORT | F SPORT tuning |
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| Front-seat treatment | Power seats; upholstery varies | Sport seats; materials vary by edition | Comfort or F SPORT seats, by member | Heated; heated and ventilated on full F SPORT | Heated and ventilated sport seats |
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| Retractable-hardtop model | IS 250C | — | IS 350C | — | — |
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| Limited-edition focus | — | Launch Edition and 500-unit edition | — | — | Crafted Line anniversary edition |
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| Notable cabin technology | Recent IS 300: 8-inch touchscreen | Premium and 500-unit edition: 10.3-inch screen and premium audio | 2026: 12.3-inch touchscreen and gauges | 8-inch touchscreen | Navigation system |
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