2022 Mercedes-Benz S-Class: What's New, Specs & Features

Last updated August 4, 2026

2022 Mercedes-Benz S-Class

The main change for the 2022 Mercedes-Benz S-Class is a narrower trim lineup: the S 560 and S 560 4MATIC were dropped. Otherwise, this is a quiet follow-up to the 2021 redesign, with the S 500 and S 580 carrying over without a major engineering or equipment overhaul.

0 in stock at Carvana

About the 2022 Mercedes-Benz S-Class

Seventh-generation W223 S-Class sedan, second U.S. model year after the 2021 redesign.

Mercedes-Benz positions the S-Class as its flagship luxury sedan and technology showcase: a full-size four-door built to make long trips quiet, comfortable, and easy whether you are driving or being driven. Its core appeal is the mix of smooth power, a hushed ride, generous rear-seat space, advanced driver aids, and a dramatic screen-heavy cabin. Against rivals, the S-Class leans hardest into serene comfort, rich materials, and new in-car tech rather than overt sportiness.

The S 500 4MATIC is the six-cylinder foundation of the range, but it still has the full flagship treatment, including massaging front seats, a 12.8-inch OLED touchscreen, augmented-reality navigation, and a broad driver-assistance suite. The S 580 4MATIC adds a twin-turbo V8 for a more effortless big-engine feel while retaining the same focus on comfort, cabin technology, and standard AWD.

What changed, by category

Powertrain and lineup
The S 560 and S 560 4MATIC trims were dropped. The remaining S 500 4MATIC kept its turbocharged 3.0-liter six-cylinder engine, while the S 580 4MATIC kept its 4.0-liter twin-turbo V8; both continued with a 9-speed automatic and AWD.

2022 Mercedes-Benz S-Class specs and features by trim

Feature
2022 Mercedes-Benz S-ClassS 500 4MATIC0 in stock
2022 Mercedes-Benz S-ClassS 580 4MATIC0 in stock
EngineV6, Twin Turbo, 3.0 LiterV8, Twin Turbo, 4.0 Liter
TransmissionAutomatic, 9-Spd 9G-TronicAutomatic, 9-Spd 9G-Tronic
DrivetrainAWDAWD
Fuel TypeGasGas
MPG City21 mpg16 mpg
MPG Highway30 mpg25 mpg
Horsepower429 hp496 hp
Torque384 lb-ft516 lb-ft
Trunk/Cargo12.9 cu-ft12.9 cu-ft
Rear Legroom43.8 in43.8 in
Seats55
Doors44
Alarm System
Automatic High Beams
Blindspot Sensors
Inflatable Seat Belts
Lane Departure Warning
Park Assist
360 Camera
Alloy Wheels
LED Headlights
Panorama Moon Roof
Rear Spoiler
Head-Up Display
Navigation System
Premium Audio
Rear DVD Entertainment System
Smartphone Interface
4-Zone Automatic Air Conditioning
Dual-Zone Climate Control
Heated Front Seats
Heated Steering Wheel
Leather Seats
Massage Rear Seat
Proximity Keyless Entry
Remote Start
Ventilated Front Seats

How the 2023 Mercedes-Benz S-Class compares

The biggest change for the 2023 Mercedes-Benz S-Class is the addition of the S 580e 4MATIC plug-in hybrid to the U.S. lineup. Otherwise, this is a quiet carryover year with no redesign or broad equipment update.

Frequently asked questions

Was the 2022 Mercedes-Benz S-Class redesigned?

No. The 2022 S-Class was the second model year of the W223 generation introduced for 2021, so it carried over without another redesign.

What changed between the 2021 and 2022 Mercedes-Benz S-Class?

The main change was the departure of the S 560 and S 560 4MATIC trims. The remaining S 500 4MATIC and S 580 4MATIC continued without a major powertrain, styling, safety, technology, or structural update.

Which Mercedes-Benz S-Class trims remained for 2022?

The 2022 gas-powered S-Class lineup consisted of the S 500 4MATIC and S 580 4MATIC. The S 500 used a turbocharged six-cylinder engine, while the S 580 used a twin-turbo V8.

Does the 2022 Mercedes-Benz S-Class have all-wheel drive?

Yes. Both remaining 2022 trims were 4MATIC models, Mercedes-Benz’s name for all-wheel drive.

Is the 2022 S-Class a major upgrade over the 2021 model?

No. The 2022 model is largely a carryover from the redesigned 2021 S-Class, aside from the narrower trim lineup. Its core engines, large OLED touchscreen, comfort features, and driver-assistance technology remained substantially the same.

2022 Mercedes-Benz S-Class Reviews

What owners are saying about the 2022 Mercedes-Benz S-Class.

4.2
2022 Mercedes-Benz S-Class
(596 reviews)
5 stars (320)
4 stars (159)
3 stars (66)
2 stars (36)
1 star (15)

About owner reviews

Carvana owner reviews are provided in partnership with Strategic Vision, one of the largest automotive consumer research providers in the U.S. Star ratings are from ranking surveys completed by owners one to six months post-purchase. Comments from owners are optional, but included here when available.

“The GPS is missing major roads. Better to use Google Maps or Waze. Don't pay a premium for the heads-up display feature that relies on the in-car navigation system. You'll be disappointed.”

PPParry P.
2022 Mercedes-Benz S-Class S500 4Matic Sedan

“well built and beautiful vehicle, but requires time to get to learn the many features. I feel that after 3 months of ownership I have just scratched the surface with lots more to learn!!”

GKGlenn K.
2022 Mercedes-Benz S-Class S580 4Matic Sedan

“I wish I had my 2020 S550 back. The entry of the car is difficult because they changed the door opening to accommodate the dash which is trying to look like a Tesla. The car has gone too far in "style over function" I actually hate it. Tesla should be trying to become Mercedes; Mercedes should not try and become Tesla.”

JKJohn K.
2022 Mercedes-Benz S-Class S580 4Matic Sedan