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2022 Mercedes-Benz CLS: What's New, Specs & Features
Last updated August 4, 2026
The most important change for the 2022 Mercedes-Benz CLS is a light mid-cycle refresh led by revised front-end styling and a standard AMG Line exterior. The U.S. lineup also narrows to the all-wheel-drive CLS 450 4MATIC.
About the 2022 Mercedes-Benz CLS
3rd generation (C257, 2019-2023), mid-cycle refresh year.
Mercedes-Benz positions the CLS as a style-led four-door coupe: a sleeker, more emotional alternative to a traditional midsize luxury sedan. The focus is on dramatic design, a rich cabin, smooth six-cylinder power, and long-distance comfort more than outright sportiness. For most shoppers, the CLS is the choice for E-Class-based luxury with a lower roofline, more visual drama, and a more special-feeling road presence.
For 2022, the CLS is a design-focused four-door coupe with a low roofline, standard AMG Line styling, and a digital luxury cabin. The sole U.S. version pairs a 362-hp turbocharged inline-6 mild hybrid with all-wheel drive, while dual 12.3-inch displays, navigation, smartphone integration, and heated memory seats highlight the interior.
What changed, by category
Styling
The front end gets a revised grille and bumper, while AMG Line exterior styling becomes standard. Mercedes-Benz also updates the interior trim and upholstery selections.
Tech
A new Nappa leather steering wheel adds touch-sensitive controls.
Structural
The rear-wheel-drive CLS 450 is dropped, leaving the all-wheel-drive CLS 450 4MATIC as the only U.S. model.
2022 Mercedes-Benz CLS specs and features by trim
| Feature | |
|---|---|
| Engine | 6-Cyl, Turbo, 3.0 Liter w/EQ Boost |
| Transmission | Automatic, 9-Spd 9G-Tronic |
| Drivetrain | AWD |
| Fuel Type | Gas |
| MPG City | 22 mpg |
| MPG Highway | 30 mpg |
| Horsepower | 362 hp |
| Torque | 369 lb-ft |
| Trunk/Cargo | 11.9 cu-ft |
| Rear Legroom | 35 in |
| Doors | 4 |
Frequently asked questions
Is the 2022 Mercedes-Benz CLS fully redesigned?
No. The 2022 CLS receives a light mid-cycle refresh within the third generation rather than a full redesign. Its main updates are revised front styling, a standard AMG Line exterior, and a new steering wheel.
Which 2022 Mercedes-Benz CLS model was sold in the U.S.?
The CLS 450 4MATIC is the only U.S. model for 2022. The rear-wheel-drive CLS 450 from 2021 was dropped, so every 2022 U.S. CLS has all-wheel drive.
Did the 2022 Mercedes-Benz CLS get a new engine?
No. The 2022 CLS 450 4MATIC carries over its 362-hp turbocharged 3.0-liter inline-6 mild-hybrid engine, nine-speed automatic transmission, and all-wheel-drive system.
What exterior changes distinguish the 2022 CLS from the 2021 model?
The 2022 CLS has a revised grille and front bumper, and the sportier AMG Line exterior treatment is standard. These visual updates are the clearest differences from the 2021 model.
Is the 2022 Mercedes-Benz CLS meaningfully different from the 2021 model?
The 2022 CLS is mainly different in appearance, cabin details, and lineup structure. Its revised nose, standard AMG Line styling, new touch-control steering wheel, and one-model U.S. lineup set it apart, but the core powertrain carries over.
2022 Mercedes-Benz CLS Reviews
What owners are saying about the 2022 Mercedes-Benz CLS.
4.3
2022 Mercedes-Benz CLS
(77 reviews)
“Electronics are complicated to use and controls especially on steering wheel are NOT user friendly.”
“The exterior and interior styling is incredible. The technological features and driver assist features are well worth the investment. The car looks great outside, too, and turns heads.”