2021 Mercedes-Benz AMG E-Class: What's New, Specs & Features
Last updated August 4, 2026

The biggest change for the 2021 Mercedes-Benz AMG E-Class is a broad mid-cycle refresh, not a full redesign. It brings updated styling, touch-operated MBUX infotainment, a new AMG steering wheel, and a more comfortable suspension setup for the E 63 S.
About the 2021 Mercedes-Benz AMG E-Class
Fifth-generation E-Class family, mid-cycle refresh year; the sedan-based generation began for 2017, with the related coupe and cabriolet following for 2018.
The AMG E-Class combines the passenger space, cabin comfort, and everyday usefulness of Mercedes’ midsize luxury car with much stronger engines, variable AWD, adaptive air suspension, and driver-adjustable performance settings. It serves shoppers who want one vehicle for commuting, long trips, and fast back-road driving. Its unusual breadth is a key distinction: the 2021 range includes sedan, coupe, cabriolet, and high-performance wagon body styles.
The E 53 is the more balanced daily driver, pairing a 429-hp mild-hybrid six-cylinder engine with variable AWD and adaptive air suspension in sedan, coupe, and convertible forms. The E 63 S is the more intense sedan or wagon, with a 603-hp twin-turbo V8, variable AWD, Drift mode, and an electronic limited-slip rear differential. Both use dual 12.3-inch displays with Apple CarPlay and Android Auto.
What changed, by category
2021 Mercedes-Benz AMG E-Class specs and features by trim
| Feature | ||
|---|---|---|
| Engine | V6, Twin Turbo, 3.0 Liter | V8, Twin Turbo, 4.0 Liter |
| Transmission | Automatic, 9-Spd w/AMG SPEEDSHIFT TCT | Automatic, 9-Spd w/AMG SPEEDSHIFT MCT |
| Drivetrain | AWD | AWD |
| Fuel Type | Gas | Gas |
| MPG City | 21–22 mpg | 16 mpg |
| MPG Highway | 27–29 mpg | 23 mpg |
| Horsepower | 429 hp | 603 hp |
| Torque | 384 lb-ft | 627 lb-ft |
| Trunk/Cargo | 9.5–13.1 cu-ft | 13.1–35 cu-ft |
| Rear Legroom | 34.1–36.2 in | 36.1–36.2 in |
| Seats | 5 | 5 |
| Doors | 2–4 | 4 |
| Adaptive Cruise Control | ||
| Adaptive Headlights | ||
| Alarm System | ||
| Automatic Emergency Braking | ||
| Automatic High Beams | ||
| Blindspot Sensors | ||
| Lane Departure Warning | ||
| Park Assist | ||
| 360 Camera | ||
| Alloy Wheels | ||
| LED Headlights | ||
| Power Moonroof | ||
| Panorama Moon Roof | ||
| Power Retractable Soft Top | ||
| Rear Spoiler | ||
| Navigation System | ||
| Premium Audio | ||
| Smartphone Interface | ||
| Aluminum Interior Trim | ||
| Dual-Zone Climate Control | ||
| Rear Air Conditioning | ||
| Heated Front Seats | ||
| Heated Rear Seats | ||
| Heated Steering Wheel | ||
| Leather Seats | ||
| Proximity Keyless Entry | ||
| Rear Window Shades | ||
| Remote Start | ||
| Ventilated Front Seats | ||
Frequently asked questions
Was the 2021 Mercedes-Benz AMG E-Class fully redesigned?
No. The 2021 AMG E-Class received a mid-cycle refresh with updated exterior styling, cabin controls, infotainment, and steering-wheel design, while the underlying generation carried over.
What infotainment change did the 2021 AMG E-Class receive?
The 2021 AMG E-Class gained touch-operated MBUX infotainment with natural-language voice control. It runs through the dual 12.3-inch displays and replaces the earlier COMAND interface.
Did the 2021 AMG E-Class engines change from 2020?
No. The E 53 retained its 429-hp mild-hybrid turbocharged inline-six, while the E 63 S retained its 603-hp twin-turbo V8.
Did the 2021 AMG E 63 S become more comfortable?
Yes. Mercedes recalibrated the E 63 S air suspension for a softer everyday ride while retaining its adaptive damping and high-performance hardware.
What equipment became standard on the 2021 AMG E-Class?
The E 53 made Park Assist and a 360-degree camera standard for 2021. The E 63 S made a heated steering wheel standard.